2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W007077
    (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone
    		Control 99.64%
    (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone is a precursor in the synthesis of benzodiazepines and is also a hydrolysis product of Clonazepam.
    (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone
  • HY-41324R
    7-keto-Deoxycholic acid (Standard)
    7-keto-Deoxycholic acid (Standard) is the analytical standard of 7-keto-Deoxycholic acid. This product is intended for research and analytical applications. 7-keto-Deoxycholic acid is a metabolite of bile acids in Clostridium absonum. 7-keto-Deoxycholic acid is also converted from Lactobacillus and Bifidobacterium with specific condition[1][2].
    7-keto-Deoxycholic acid (Standard)
  • HY-W509381
    4-Hydroxyindole-3-acetic acid
    4-Hydroxyindole-3-acetic acid (4HIAA) is a metabolite of Psilocybin and Psilocin.
    4-Hydroxyindole-3-acetic acid
  • HY-G0009
    Ritonavir metabolite
    		99.09%
    Ritonavir metabolite is a metabolite of Ritonavir, which is a HIV protease inhibitor.
    Ritonavir metabolite
  • HY-156836
    Tyramine O-sulfate
    Tyramine O-sulfate (Tyramine sulfate) is a metabolite of Tyramine (HY-W007606) in urinary. Tyramine O-sulfate can be used as a marker for melancholia.
    Tyramine O-sulfate
  • HY-W017115
    4-Methoxybenzenecarbothioamide
    4-Methoxybenzenecarbothioamide is a synthetic intermediate useful for pharmaceutical synthesis, which can be synthesized by 4-methoxy benzamide and phosphorus pentasulfide reactions.
    4-Methoxybenzenecarbothioamide
  • HY-113257
    Dopamine 4-sulfate
    Dopamine 4-sulfate (DA-4S) is an inactive metabolite of the catecholamine dopamine. It is formed from dopamine by the sulfotransferase (SULT) isoform SULT1A3. Dopamine 4-O-sulfate is found at lower levels in the brain and circulation than dopamine 3-O-sulfate.
    Dopamine 4-sulfate
  • HY-W099331
    Monoethylglycinexylidide hydrochloride
    		98.82%
    Monoethylglycinexylidide (MEGX) hydrochloride is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver. Monoethylglycinexylidide has proven to be a highly sensitive indicator of hepatic dysfunction, especially in the field of liver transplantation.
    Monoethylglycinexylidide hydrochloride
  • HY-W015169S
    5-Methoxytryptamine-d4
    		99.7%
    5-Methoxytryptamine-d4 (O-Methylserotonin-d4) is the deuterium labeled 5-Methoxytryptamine (HY-W015169). 5-Methoxytryptamine, a metabolite of Melatonin, is a nonselective 5-HT receptor agonist. 5-Methoxytryptamine has no affinity for the 5-HT3 receptor. 5-Methoxytryptamine is also a potent antioxidant and has radioprotective action.
    5-Methoxytryptamine-d<sub>4</sub>
  • HY-W010593
    Ethylenethiourea
    		≥98.0%
    Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active.
    Ethylenethiourea
  • HY-W016221S1
    6-Hydroxy Chlorzoxazone-15N,d2
    6-Hydroxy Chlorzoxazone-15N,d2 is the 15N and deuterium labeled 6-Hydroxy Chlorzoxazone (HY-W016221).
    6-Hydroxy Chlorzoxazone-<sup>15</sup>N,d<sub>2</sub>
  • HY-N15317
    Phocaecholic acid
    		98.0%
    Phocaecholic acid (β-Phocaecholic acid) is a bile acid found in duck bile. Phocaecholic acid can be excreted into bile and partially decarboxylated to nor-chenodeoxycholic acid in rats. Phocaecholic acid is promising for research of bile acid metabolism and related diseases.
    Phocaecholic acid
  • HY-G0003
    Iloperidone metabolite Hydroxy Iloperidone
    		99.97%
    Iloperidone metabolite Hydroxy Iloperidone (P88; Hydroxy Iloperidone) is a metabolite of Iloperidone, which is an atypical antipsychotic.
    Iloperidone metabolite Hydroxy Iloperidone
  • HY-W045132
    N-Desbutyl Bupivacaine
    N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist.
    N-Desbutyl Bupivacaine
  • HY-100048
    Acetylisoniazid
    Acetylisoniazid is a primary Isoniazid (HY-B0329) metabolite mediated by N-acetyltransferase (NAT). Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity.
    Acetylisoniazid
  • HY-19657S
    Oxypurinol-13C,15N2
    Oxypurinol-13C,15N2 is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.
    Oxypurinol-<sub>13</sub>C,<sub>15</sub>N<sub>2</sub>
  • HY-G0008A
    O-Desmethyl Mebeverine alcohol hydrochloride
    		98.0%
    O-Desmethyl Mebeverine alcohol hydrochloride is a metabolite of Mebeverine, which is a potent α1 repector inhibitor, causing relaxation of the gastrointestinal tract.
    O-Desmethyl Mebeverine alcohol hydrochloride
  • HY-W585952
    Salicylic acid 2-O-β-D-glucoside
    Salicylic acid 2-O-β-D-glucoside (SA-2-O-β-D-glucoside) is the predominant glycosylated metabolite of Salicylic Acid (HY-B0167).
    Salicylic acid 2-O-β-D-glucoside
  • HY-124414A
    4'-Hydroxytamoxifen TFA
    		99.43%
    4'-Hydroxytamoxifen TFA is a salt form of a metabolite of Tamoxifen. 4'-Hydroxytamoxifen TFA has a higher affinity for ER than Tamoxifen. 4'-Hydroxytamoxifen TFA induces non-apoptotic cytotoxicity in human endometrial adenocarcinoma cells.
    4'-Hydroxytamoxifen TFA
  • HY-15550S1
    4'-Hydroxy diclofenac-13C6
    4'-Hydroxy diclofenac-13C6 is the 13C labeled 4'-Hydroxy diclofenac. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties.
    4'-Hydroxy diclofenac-<sup>13</sup>C<sub>6</sub>
Cat. No. Product Name / Synonyms Application Reactivity